This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The package insert is also submitted in pdf and spl format. We have just found the perfect template for us to use in our powerpoint presentation and we just wish that the certain template was available in another color. Organic powerpoint template powerpoint, diagrams, word, and. The recommended dose of oncaspar is 2,500 international unitsm2 intramuscularly or intravenously. Baxter to buy oncaspar product portfolio from sigmatau. Pegaspargase oncaspar childrens education materials. Definition from the nci drug dictionary detailed scientific definition and other names for this drug. Pharmacodynamics and safety of intravenous pegaspargase during. Common drugs affecting coagulation drug use aspirin thromboprophylaxis in coronary artery disease nsaids analgesics used widely in arthritis clopidogrel antiplatelet used in coronary artery disease warfarin thromboprophylaxis in atrial fibrillation, post. Identical weekly doses of filtered wildtype asnase 0.
Each extended release tablet filmcoated tablet contains verapamil hydrochloride usp 240mg. Oncaspar can be given by intramuscular im injection or intravenous iv infusion. Visiting standards have been updated to allow only two legal guardians at the bedside during a patients stay. Drug preparation and administration hematologyoncology. Word will convert the pdf to editable text and you can then copy and paste that text into your office document. When oncaspar is administered intramuscularly, the volume at a single injection site should be limited to 2 ml. Baxter to buy oncaspar product portfolio from sigmatau finanziaria. Pegaspargase oncaspar is a modified form of native e coli asparaginase in which the enzyme is covalently linked to polyethylene glycol. Side effects of oncaspar pegaspargase, warnings, uses. Oncaspar 750 uml solution for injectioninfusion summary. For smaller volumes, the preferred route of administration is intramuscular.
Oncaspar, 48 patients 81% received all 3 planned doses of oncaspar, 6 10% received 2 doses, 4 7% received 1 dose, and 1 patient 2% did not receive the assigned treatment. Discover everything scribd has to offer, including books and audiobooks from major publishers. Administer integrilinby volume according to patient weightsee table1. Winner of the standing ovation award for best powerpoint templates from presentations magazine. When oncaspar is given by intramuscular injection the volume injected at one site should not exceed 2 ml in children and adolescents and 3 ml in adults. The recommended dose of oncaspar for children with a body surface area. Notably, the safety profiles between the newly diagnosed and relapsed subsets and between iv and im administration were consistent with the findings for the overall population. For the full list of side effects reported with oncaspar, see the package leaflet. Download the inkscape application its free and is available for various platforms go here and convert your. Each vial of oncaspar contains 3,750 international units of pegaspargase in 5 ml of solution. Highlights of prescribing information coadministration of. May 14, 2015 baxter to buy oncaspar product portfolio from sigmatau finanziaria. If the volume to be administered is greater than 2 ml, multiple injection sites should be used.
Fulltext pdf costeffectiveness of drugeluting stents in elderly patients with coronary artery disease. The pdf file should be the first option within the insert dialog window. It is recommended to use young cultures 1824 hours old. One main difference that you may experiment while working with powerpoint web apps is the concept of themes and variants. Using a pipette or psipette, pick up 14 colonies of identical morphology from the agar plate, either by suction or by successive touches. Oncaspar reference guide for safe and effective use from the american society of. Qualitative and quantitative composition 5 ml solution for injection contain pegaspargase equivalent to 3750 i. Documentation label intravenous infusion bottle and record on fluid balance sheet, include. A prospective study on drug monitoring of pegasparaginase and erwinia asparaginase. Our analysis also provided additional information about the safety profile of asparaginase erwinia chrysanthemi therapy in patient subpopulations. Oncaspar should be discontinued in the case of anaphylaxis or serious allergic reactions, thrombosis, or pancreatitis.
Pegaspargase is also being studied in the treatment of other types of cancer. Blank staring into space empty look in eyes rapid blinking eyes rolling upward periods of unresponsiveness inability to pay attention repetitive ticlike movements of body parts, usually head, arms, legs total body jerking with eyes rolled back in head mouth movements with a dazed look frothing at mouth loss of consciousness. Ppt heparin powerpoint presentation free to view id. Tevas generic medications are available in most pharmacies across the united states, though not all pharmacies carry the same teva medications. Ref 20 050 h 20 ne ivd florida international university. Data sources include ibm watson micromedex updated 10 apr 2020, cerner multum updated 6 apr 2020. Baxalta announced that the european commission has granted marketing authorization for use of oncaspar as a combination therapy for acute lymphoblasti. Study 2 is an ongoing, multifactorial design study in which all patients received oncaspar as a component of various.
Center the spike within the circle on the stopper top. Because of the possible risk to the infant, breastfeeding while using this drug is not recommended. Chapter 1 slides from management a pacific rim focus. Jan 11, 2019 the recommended dose of oncaspar is 2,500 ium 2 intramuscularly im or intravenously iv. This nice powerpoint template designed in pale blue and green colors with plants in the petri dishes will fit presentations on scientific experiments in biology and microbiology, genetics, selection, and the like. Open your powerpoint presentation on the page you want to insert the pdf within. Ppt medication administration powerpoint presentation. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. History of serious thrombosis with prior lasparaginase therapy. How to insert a pdf into powerpoint online tech tips. Oncaspar is contraindicated in patients with a history of serious allergic reactions to oncaspar, and in patients with a history of serious thrombosis, pancreatitis, or serious hemorrhagic events with prior lasparaginase therapy.
Free marketing strategy powerpoint template can be used for marketing presentations requiring a nice design and powerpoint background to make attractive business plans and marketing plans including slides with marketing diagrams like 4p marketing mix or action plan and timelines or roadmap slides. Guidelines for asparaginase administration asparaginase is an antineoplastic agent used most effectively and commonly in pediatrics in the treatment of acute lymphocytic leukemia all, lymphoblastic lymphoma, and acute. Insert pdf content into your presentation either as a picture that shows on your slide, or as a document that you can open during your slide show. It is given by injection shot into the muscle or as an infusion in the hospital or clinic. Times new roman tahoma arial symbol andy verdana arial black default design cs chemdraw drawing powerpoint presentation powerpoint presentation powerpoint presentation powerpoint presentation powerpoint presentation powerpoint presentation powerpoint presentation powerpoint presentation powerpoint presentation powerpoint presentation powerpoint. Insert pdf file content into a powerpoint presentation powerpoint. Oncasparoo should be given over a period of i to 2 hours in 100 ml of sodium chloride or. To form the plurals of hyphenated nouns, add s only to the first word. Oncaspar pegaspargase is indicated as a component of a multiagent chemotherapeutic regimen for. Store in a tight, lightresistant container see usp. Tech support scams are an industrywide issue where scammers trick you into paying for unnecessary technical support services.
Medlineplus information on pegaspargase a lay language summary of important information about this drug that may include the following. Click the image and it will be inserted into the slide. Treatment of pegylated asparaginaseinduced hypertriglyceridemia. Heparin is a heterogeneous mixture of unbranced polysaccharide chains.
Show possession by adding s at the end of the word. Engineered binding to erythrocytes induces immunological. Third year organic chemistry co303 natural product chemistry amino acids, peptides and proteins convener. Pegaspargase pegasparjace destroys leukemia cancer cells in the first growth g 1 phase of cell life.
For purpose of this study, the drug was given as a single intravenous dose. In the following article we dive into how to create a microsoft word label template from scratch option a but we want you to know thats not your only option. Themes and variants in powerpoint web apps powerpoint web apps is the online free version of powerpoint that has the new metro interface and features that you will find in the office 20 version. Asparaginase administration page 4 of 5 the need for prophylactic use of allopurinol, hydration and sodium bicarbonate to prevent hyperuricemia from possible tumour lysis at initial administration will be.
Jan 16, 2014 our analysis also provided additional information about the safety profile of asparaginase erwinia chrysanthemi therapy in patient subpopulations. Rules for compound nouns hyphenated nouns add to the confusion. When oncaspar is administered 1m, the volume at a single injection site should be limited to 2 ml. Jan 19, 2016 baxalta announced that the european commission has granted marketing authorization for use of oncaspar as a combination therapy for acute lymphoblasti.
We offer a complete collection of label templates including popular cd address shipping round mailing for free in several formats doc pdf eps and more. The fda previously approved oncaspar only for patients with all who were unable to receive the cancer drug lasparaginase because of an allergy. Medac to market enzons oncaspar in europe and russia. The diluted solution can be given together with an alreadyrunning infusion of either sodium chloride. If youre looking to insert the contents of your pdf file into an office file, as opposed to simply inserting the pdf as an attachment, then your best bet is to open that pdf with word 20 or 2016. The patient was diagnosed with druginduced liver injury due to peglasparaginase after a thorough evaluation for all other causes and. Mar 19, 20 documentation label intravenous infusion bottle and record on fluid balance sheet, include. Jul 23, 2019 provides accurate and independent information on more than 24,000 prescription drugs, overthecounter medicines and natural products. Name of the medicinal product oncaspar solution for injection 2.
It is unknown if this drug passes into breast milk. Doctors give trusted answers on uses, effects, sideeffects, and cautions. Tell your doctor all medications and supplements you use. Fawaz aldabbagh primary, secondary, tertiary and quaternary structures of proteins. The recommended dose of oncaspar is 2,500 international unitsm. Highlights of prescribing information these highlights do. You can help protect yourself from scammers by verifying that the contact is a microsoft agent or microsoft employee and that the phone number is an official microsoft global customer service number. For the full list of restrictions, see the package leaflet. Baxalta granted eu marketing authorization for oncaspar. When using an intravenous infusion pump, administer integrilin undiluted directly from the 100ml vial. There is limited information on desensitization protocols in the setting of anaphylaxis to both pegaspargase and erwiniaderived products. During pregnancy, oncaspar should be used only when prescribed.
Oncaspar pegaspargase injection, for intramuscular or intravenous use. Detecting and treating asparaginaserelated toxicities in. Oncaspar fda prescribing information, side effects and uses. Although there may not be an apparent change in the appearance of the drug, oncaspars activity is destroyed after freezing. The recommended dose of oncaspar is 2,500 ium 2 intramuscularly im or intravenously iv.
Powerpoint web apps is the online free version of powerpoint that has the new metro interface and features that you will find in the office 20 version. A polymer is a chemical compound or mixture of compounds consisting of repeating structural units. Showing plural possession add only to show possession for plural nouns ending in s. P030 desensitization protocol for pegaspargase anaphylaxis. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. History of serious hypersensitivity reactions, including anaphylaxis, to oncaspar or to any of the excipients. A seizure is a brief, temporary disturbance in the electrical activity of the brain and may affect. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Zebro formerly woldegiorgis on lovenox package insert. Pegaspargase in the treatment of acute lymphoblastic leukemia.
Direct costs hospitalization, drug administration, allergic reactions management were derived from gazzetta ufficiale. Using a pipette or psipette, pick up 14 colonies of identical morphology from the agar plate, either by suction or by. Each milliliter contains 750 international units of pegaspargase, dibasic sodium phosphate, usp 5. Oncaspar must not be used in patients with severe liver disease, patients who have ever had pancreatitis or those who have had severe bleeding or serious blood clots following asparaginase treatment. Intravenous infusion of oncaspar is usually given over a period of 1 to 2 hours in 100 ml sodium chloride 9 mgml 0.
Safety profile of asparaginase erwinia chrysanthemi in a. Occasionally, the package insert component of product labeling for drugs that have received fda approval for commercial use is prefaced by prominent precautionary and warning summaries circumscribed by a rectangular border, commonly referred to as black box warnings, or, simply, boxed warnings. Do not administer oncaspar if there is any indication that the drug has been frozen. Please click here for full prescribing information. Although prior fda labeling submission requirements have been in the ms word and pdf formats, the fda now requires the package insert portion of. The fda expanded the approved use of onscapar to include treating children and adults with newly diagnosed acute lymphoblastic leukemia all as part of a multipledrug chemotherapy regimen. Preparations from porcine or bovine intestinal mucus. Jan, 2014 tech support scams are an industrywide issue where scammers trick you into paying for unnecessary technical support services. It should be administered no more frequently than every 14 days. Oncaspar is a strong strategic fit for our rapidly expanding oncology business, as it complements our research. Oncaspar is indicated as a component of a multiagent chemotherapeutic regimen for the treatment of pediatric and adult patients with all and hypersensitivity to native forms of lasparaginase. Open the emf file in powerpoint and ungroup twice to edit it. If you think someone in your family has been exposed to covid19, stay home and contact your health care provider for next steps.
As an organization accredited by the accme, medscape, llc, requires everyone who is in a position to control the content of an education activity to disclose all relevant financial relationships with any commercial interest. Oncaspar may interact with vincristine, prednisone, or methotrexate. Common drugs affecting coagulation drug use aspirin thromboprophylaxis in coronary artery disease nsaids analgesics used widely in arthritis clopidogrel antiplatelet used in coronary artery disease warfarin thromboprophylaxis in atrial fibrillation, post heart valve replacement, dvt, or. Oncaspar pegaspargase is indicated as a component of a multiagent chemotherapeutic regimen for the treatment of pediatric and adult patients with. This nice powerpoint template designed in pale blue and green colors with plants in the petri dishes will fit presentations on scientific experiments in biology an. Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience. The governorgenerals car my brotherinlaws boat but. A free powerpoint ppt presentation displayed as a flash slide show on id.
The proposed package insert document is usually created in microsoft word and submitted as part of the final labeling folder. Hit start conversion and then click download once its ready. Organic powerpoint template powerpoint, diagrams, word. Oncaspar should be administered no more frequently than every 14 days. The costeffectiveness of pegaspargase for firstline treatment of.
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